Human EZH1 (Enhancer Of Zeste Homolog 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015101)

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STJE0015101
€528.60 - €737.40
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Short Description :This EZH1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.113ng/mL
Detection Limit:0.312-20ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:3 hrs
Gene Symbol:EZH1
Gene ID:2145
Uniprot ID:EZH1_HUMAN
Immunogen Region:Ready-To-Use
Sample Type:tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Protein Name Histone-Lysine N-Methyltransferase Ezh1
Enx-2
Enhancer Of Zeste Homolog 1
Database Links
Cellular Localisation Nucleus
Colocalizes With Trimethylated 'Lys-27' Of Histone H3
Alternative ELISA Names Histone-Lysine N-Methyltransferase Ezh1 ELISA kit
Enx-2 ELISA kit
Enhancer Of Zeste Homolog 1 ELISA kit
EZH1 ELISA kit
KIAA0388 ELISA kit
output

Information sourced from Uniprot.org