Human EZH1 (Enhancer Of Zeste Homolog 1) Sandwich ELISA Kit (STJE0008722)
SPECIFICATIONS
General Information
| Short Description | This EZH1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.113ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | EZH1 |
| Gene ID | 2145 |
| Uniprot ID | EZH1_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
| Protein Name | Histone-Lysine N-Methyltransferase Ezh1Enx-2Enhancer Of Zeste Homolog 1 |
| Database Links | |
| Cellular Localisation | NucleusColocalizes With Trimethylated 'Lys-27' Of Histone H3 |
| Alternative ELISA Names | Histone-Lysine N-Methyltransferase Ezh1 ELISA kitEnx-2 ELISA kitEnhancer Of Zeste Homolog 1 ELISA kitEZH1 ELISA kitKIAA0388 ELISA kit |
| output |
Information sourced from Uniprot.org