Human EXOC7 protein (Recombinant) (N-His) (STJP007777)

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STJP007777
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human EXOC7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: EXOC7
Gene ID: 23265
Uniprot ID: EXOC7_HUMAN
Immunogen Region: Met1-Gly246
Immunogen: Homo sapiens (Human)
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development.
Protein Name Exocyst Complex Component 7
Exocyst Complex Component Exo70
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-264876
Reactome: R-HSA-5620916
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Peripheral Membrane Protein
Midbody
Midbody Ring
Translocates
As A Preformed Complex With Exoc3/Sec6 And Exoc4/Sec8
To The Plasma Membrane In Response To Insulin Through The Activation Of Arhq
Colocalizes With Cntrl/Centriolin At The Midbody Ring
Alternative Protein Names Exocyst Complex Component 7 protein
Exocyst Complex Component Exo70 protein
EXOC7 protein
EXO70 protein
KIAA1067 protein

Information sourced from Uniprot.org