Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development. |
Protein Name | Exocyst Complex Component 7Exocyst Complex Component Exo70 |
Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-264876Reactome: R-HSA-5620916 |
Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinMidbodyMidbody RingTranslocatesAs A Preformed Complex With Exoc3/Sec6 And Exoc4/Sec8To The Plasma Membrane In Response To Insulin Through The Activation Of ArhqColocalizes With Cntrl/Centriolin At The Midbody Ring |
Alternative Protein Names | Exocyst Complex Component 7 proteinExocyst Complex Component Exo70 proteinEXOC7 proteinEXO70 proteinKIAA1067 protein |
Information sourced from Uniprot.org