Human ESRRG protein (Recombinant) (N-His) (STJP016018)

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STJP016018
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Short Description :Recombinant-Human ESRRG-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:ESRRG
Gene ID:2104
Uniprot ID:ERR3_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Asn235-Val458
Post Translational Modifications Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
Function Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle.
Protein Name Estrogen-Related Receptor Gamma
Err Gamma-2
Estrogen Receptor-Related Protein 3
Nuclear Receptor Subfamily 3 Group B Member 3
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Protein Names Estrogen-Related Receptor Gamma protein
Err Gamma-2 protein
Estrogen Receptor-Related Protein 3 protein
Nuclear Receptor Subfamily 3 Group B Member 3 protein
ESRRG protein
ERR3 protein
ERRG2 protein
KIAA0832 protein
NR3B3 protein

Information sourced from Uniprot.org

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