Human ERVK-6/HERV-K Env protein (Recombinant) (N-His) (STJP009290)

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STJP009290
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ERVK-6/HERV-K Env-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ERVK-6
Uniprot ID: ENK6_HUMAN
Immunogen Region: Leu90-Thr632
Immunogen: Homo sapiens (Human)
Post Translational Modifications Specific enzymatic cleavages in vivo yield the mature SU and TM proteins.
Function Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties. SU mediates receptor recognition. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Protein Name Endogenous Retrovirus Group K Member 6 Env Polyprotein
Envk2 Protein
Envelope Polyprotein
Herv-K(C7 Envelope Protein
Herv-K(Hml-2.Hom Envelope Protein
Herv-K108 Envelope Protein
Herv-K_7p22.1 Provirus Ancestral Env Polyprotein Cleaved Into - Surface Protein
Su - Transmembrane Protein
Tm
Cellular Localisation Transmembrane Protein: Cell Membrane
Single-Pass Type I Membrane Protein
Surface Protein: Cell Membrane
Peripheral Membrane Protein
The Surface Protein Is Not Anchored To The Membrane
But Localizes To The Extracellular Surface Through Its Binding To Tm
Endogenous Retrovirus Group K Member 6 Env Polyprotein: Virion
Alternative Protein Names Endogenous Retrovirus Group K Member 6 Env Polyprotein
Envk2 Protein protein
Envelope Polyprotein
Herv-K(C7 Envelope Protein protein
Herv-K(Hml-2.Hom Envelope Protein protein
Herv-K108 Envelope Protein protein
Herv-K_7p22.1 Provirus Ancestral Env Polyprotein Cleaved Into - Surface Protein protein
Su - Transmembrane Protein protein
Tm protein
ERVK-6 protein
ERVK6 protein

Information sourced from Uniprot.org

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