• Human ERLIN1 (ER Lipid Raft Associated Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015080)

Human ERLIN1 (ER Lipid Raft Associated Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015080)

SKU:
STJE0015080

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.107ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This ERLIN1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ERLIN1
Gene ID: 10613
Uniprot ID: ERLN1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine.
Post Translational Modifications Deubiquitinated by USP25.leading to stabilization.
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex. (Microbial infection) Required early in hepatitis C virus (HCV) infection to initiate RNA replication, and later in the infection to support infectious virus production.
Protein Name Erlin-1
Endoplasmic Reticulum Lipid Raft-Associated Protein 1
Protein Ke04
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1
Spfh Domain-Containing Protein 1
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5678895
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative ELISA Names Erlin-1 ELISA kit
Endoplasmic Reticulum Lipid Raft-Associated Protein 1 ELISA kit
Protein Ke04 ELISA kit
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1 ELISA kit
Spfh Domain-Containing Protein 1 ELISA kit
ERLIN1 ELISA kit
C10orf69 ELISA kit
KE04 ELISA kit
KEO4 ELISA kit
SPFH1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance