Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human EPSTI1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | EPSTI1 |
Gene ID: | 94240 |
Uniprot ID: | ESIP1_HUMAN |
Immunogen Region: | Asn73-Glu280 |
Immunogen: | Homo sapiens (Human) |
Function | Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages. |
Protein Name | Epithelial-Stromal Interaction Protein 1 |
Database Links | Reactome: R-HSA-9696273 |
Alternative Protein Names | Epithelial-Stromal Interaction Protein 1 proteinEPSTI1 protein |
Information sourced from Uniprot.org