Human EPN1 protein (Recombinant) (N-His) (STJP006294)

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STJP006294
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human EPN1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: EPN1
Gene ID: 29924
Uniprot ID: EPN1_HUMAN
Immunogen Region: Pro279-Gly437
Immunogen: Homo sapiens (Human)
Function Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis.
Protein Name Epsin-1
Eh Domain-Binding Mitotic Phosphoprotein
Eps-15-Interacting Protein 1
Database Links Reactome: R-HSA-182971
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Nucleus
Membrane
Clathrin-Coated Pit
Associated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are Forming
Colocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma Membrane
Detected In Presynaptic Nerve Terminals And In Golgi Stacks
May Shuttle To The Nucleus When Associated With Zbtb16/Znf145
Alternative Protein Names Epsin-1 protein
Eh Domain-Binding Mitotic Phosphoprotein
Eps-15-Interacting Protein 1 protein
EPN1 protein

Information sourced from Uniprot.org

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