Human ENTPD5 protein (Recombinant) (N-His) (STJP010729)

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STJP010729
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ENTPD5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ENTPD5
Gene ID: 957
Uniprot ID: ENTP5_HUMAN
Immunogen Region: Asn25-His428
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.high-mannose type. Glycosylation is not essential for enzymatic activity.
Function Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP. In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER.
Protein Name Nucleoside Diphosphate Phosphatase Entpd5
Cd39 Antigen-Like 4
Er-Udpase
Ectonucleoside Triphosphate Diphosphohydrolase 5
Ntpdase 5
Guanosine-Diphosphatase Entpd5
Gdpase Entpd5
Inosine Diphosphate Phosphatase Entpd5
Nucleoside Diphosphatase
Uridine-Diphosphatase Entpd5
Udpase Entpd5
Database Links Reactome: R-HSA-8850843
Reactome: R-HSA-9660826
Cellular Localisation Endoplasmic Reticulum
Secreted
Alternative Protein Names Nucleoside Diphosphate Phosphatase Entpd5 protein
Cd39 Antigen-Like 4 protein
Er-Udpase protein
Ectonucleoside Triphosphate Diphosphohydrolase 5 protein
Ntpdase 5 protein
Guanosine-Diphosphatase Entpd5 protein
Gdpase Entpd5 protein
Inosine Diphosphate Phosphatase Entpd5 protein
Nucleoside Diphosphatase protein
Uridine-Diphosphatase Entpd5 protein
Udpase Entpd5 protein
ENTPD5 protein
CD39L4 protein
PCPH protein

Information sourced from Uniprot.org

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