| Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination. |
| Function | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism. |
| Protein Name | Ectoderm-Neural Cortex Protein 1Enc-1Kelch-Like Protein 37Nuclear Matrix Protein Nrp/BP53-Induced Gene 10 Protein |
| Cellular Localisation | Nucleus MatrixCytoplasmCytoskeleton |
| Alternative Protein Names | Ectoderm-Neural Cortex Protein 1 proteinEnc-1 proteinKelch-Like Protein 37 proteinNuclear Matrix Protein Nrp/B proteinP53-Induced Gene 10 Protein proteinENC1 proteinKLHL37 proteinNRPB proteinPIG10 protein |
Information sourced from Uniprot.org
