| Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1. |
| Protein Name | Zinc Phosphodiesterase Elac Protein 1Deleted In Ma29Elac Homolog Protein 1Ribonuclease Z 1Rnase Z 1Trna 3 Endonuclease 1Trnase Z 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleusMainly Cytosolic |
| Alternative Protein Names | Zinc Phosphodiesterase Elac Protein 1 proteinDeleted In Ma29 proteinElac Homolog Protein 1 proteinRibonuclease Z 1 proteinRnase Z 1 proteinTrna 3 Endonuclease 1 proteinTrnase Z 1 proteinELAC1 proteinD29 protein |
Information sourced from Uniprot.org