Human ELAC1 protein (Recombinant) (His-Tag) (STJP019186)

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STJP019186
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ELAC1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: ELAC1
Gene ID: 55520
Uniprot ID: RNZ1_HUMAN
Immunogen Region: 1-363aa
Accession Number: NP_061166
Immunogen: Human
Immunogen Sequence: MSMDVTF LGTGAAYPSP TRGASAVVLR CEGECWLFDC GEGTQTQLMK SQLKAGRITK IFITHLHGDH FFGLPGLLCT ISLQSGSMVS KQPIEIYGPV GLRDFIWRTM ELSHTELVFH YVVHELVPTA DQCPAEELKE FAHVNRADSP PKEEQGRTIL LDSEENSYLL FDDEQFVVKA FRLFHRIPSF GFSVVEKKRP GKLNAQ
Tissue Specificity Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Function Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1.
Protein Name Zinc Phosphodiesterase Elac Protein 1
Deleted In Ma29
Elac Homolog Protein 1
Ribonuclease Z 1
Rnase Z 1
Trna 3 Endonuclease 1
Trnase Z 1
Database Links
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Mainly Cytosolic
Alternative Protein Names Zinc Phosphodiesterase Elac Protein 1 protein
Deleted In Ma29 protein
Elac Homolog Protein 1 protein
Ribonuclease Z 1 protein
Rnase Z 1 protein
Trna 3 Endonuclease 1 protein
Trnase Z 1 protein
ELAC1 protein
D29 protein

Information sourced from Uniprot.org