Human eIF-4H/EIF4H protein (Recombinant) (His-Tag) (STJP017672)

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STJP017672
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Short Description :Recombinant-Human eIF-4H/EIF4H-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:EIF4H
Gene ID:7458
Uniprot ID:IF4H_HUMAN
Accession Number:NP_071496
Immunogen:Human
Immunogen Region:1-248aa
Immunogen Sequence:MADFDT YDDRAYSSFG GGRGSRGSAG GHGSRSQKEL PTEPPYTAYV GNLPFNTVQG DIDAIFKDLS IRSVRLVRDK DTDKFKGFCY VEFDEVDSLK EALTYDGALL GDRSLRVDIA EGRKQDKGGF GFRKGGPDDR GMGSSRESRG GWDSRDDFNS GFRDDFLGGR GGSRPGDRRT GPPMGSRFRD GPPLRGSNMD FREPTE
Tissue Specificity The short isoform is the predominant isoform and is expressed alone in liver and skeletal muscle. Both isoforms are expressed in fibroblast, spleen, testis and bone marrow. Levels are high in lung and pancreas and low in heart, frontal cortex and kidney.
Function Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
Protein Name Eukaryotic Translation Initiation Factor 4h
Eif-4h
Williams-Beuren Syndrome Chromosomal Region 1 Protein
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-72649
Reactome: R-HSA-72662
Reactome: R-HSA-72702
Reactome: R-HSA-72706
Cellular Localisation Cytoplasm
Perinuclear Region
Alternative Protein Names Eukaryotic Translation Initiation Factor 4h protein
Eif-4h protein
Williams-Beuren Syndrome Chromosomal Region 1 Protein protein
EIF4H protein
KIAA0038 protein
WBSCR1 protein
WSCR1 protein

Information sourced from Uniprot.org

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