| Short Description : | Recombinant-Human EF-1 delta/EEF1D-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EEF1D |
| Gene ID: | 1936 |
| Uniprot ID: | EF1D_HUMAN |
| Accession Number: | NP_001951 |
| Immunogen: | Human |
| Immunogen Region: | 1-281aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MATNFLAHEK IWFDKFKYDD AERRFYEQMN GPVAGASRQE NGASVILRDI ARARENIQKS LAGSSGPGAS SGTSGDHGEL VVRIASLEVE NQSLRGVVQE LQQAISKLEA RLNVLEKSSP GHRATAPQTQ HVSPMRQVEP PAKKPATPAE DDEDDDIDLF GSDNEEEDKE AAQLREERLR QYAEKKAKKP ALVAKSSILL DVKPWDDE |
| Tissue Specificity | Isoform 2 is specifically expressed in brain, cerebellum and testis. |
| Function | Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). |
| Protein Name | Elongation Factor 1-DeltaEf-1-DeltaAntigen Ny-Co-4 |
| Database Links | Reactome: R-HSA-156842 |
| Cellular Localisation | Isoform 2: Nucleus |
| Alternative Protein Names | Elongation Factor 1-Delta proteinEf-1-Delta proteinAntigen Ny-Co-4 proteinEEF1D proteinEF1D protein |
Information sourced from Uniprot.org