| Function | Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. |
| Protein Name | Eukaryotic Elongation Factor 2 KinaseEef-2 KinaseEef-2kCalcium/Calmodulin-Dependent Eukaryotic Elongation Factor 2 Kinase |
| Database Links | Reactome: R-HSA-166208 |
| Alternative Protein Names | Eukaryotic Elongation Factor 2 Kinase proteinEef-2 Kinase proteinEef-2k proteinCalcium/Calmodulin-Dependent Eukaryotic Elongation Factor 2 Kinase proteinEEF2K protein |
Information sourced from Uniprot.org