Human EDNRB/ETRB protein (Recombinant) (N-GST & C-His) (STJP008849)

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STJP008849
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human EDNRB/ETRB-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: EDNRB
Gene ID: 1910
Uniprot ID: EDNRB_HUMAN
Immunogen Region: Glu236-Thr271
Immunogen: Homo sapiens (Human)
Post Translational Modifications Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405.
Function Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Name Endothelin Receptor Type B
Et-B
Et-Br
Endothelin Receptor Non-Selective Type
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-9856649
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalized After Activation By Endothelins
Alternative Protein Names Endothelin Receptor Type B protein
Et-B protein
Et-Br protein
Endothelin Receptor Non-Selective Type protein
EDNRB protein
ETRB protein

Information sourced from Uniprot.org

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