| Tissue Specificity | Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach. |
| Function | Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14). |
| Protein Name | Dual Specificity Protein Phosphatase 23Low Molecular Mass Dual Specificity Phosphatase 3Ldp-3Vh1-Like Phosphatase Z |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleusMainly CytosolicAlso Nuclear |
| Alternative Protein Names | Dual Specificity Protein Phosphatase 23 proteinLow Molecular Mass Dual Specificity Phosphatase 3 proteinLdp-3 proteinVh1-Like Phosphatase Z proteinDUSP23 proteinLDP3 proteinVHZ protein |
Information sourced from Uniprot.org