Name: Human DUSP1 protein (Recombinant) (C-His) (STJP014465)
SKU: STJP014465-100
Price: 333.5 GBP
Availability: InStock

Human DUSP1 protein (Recombinant) (C-His) (STJP014465)

SKU:

STJP014465-100

£333.50

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Host:	E.coli
Applications:	ELISA/WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human DUSP1-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range:	Reconstitute in sterile water for a stock solution.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	Please contact us for this information.

Post Translational Modifications	Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. 'Lys-48'-linked polyubiquitinated by NEURL3, leading to proteasomal degradation.
Function	Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name	Dual Specificity Protein Phosphatase 1 Dual Specificity Protein Phosphatase Hvh1 Mitogen-Activated Protein Kinase Phosphatase 1 Map Kinase Phosphatase 1 Mkp-1 Protein-Tyrosine Phosphatase Cl100
Database Links	Reactome: R-HSA-112409 Reactome: R-HSA-5675221
Cellular Localisation	Nucleus
Alternative Protein Names	Dual Specificity Protein Phosphatase 1 protein Dual Specificity Protein Phosphatase Hvh1 protein Mitogen-Activated Protein Kinase Phosphatase 1 protein Map Kinase Phosphatase 1 protein Mkp-1 protein Protein-Tyrosine Phosphatase Cl100 protein DUSP1 protein CL100 protein MKP1 protein PTPN10 protein VH1 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP006950	Human CD63 protein (Recombinant) (C-His) (STJP006950)	Mammalian Cells
STJP010507	Human FLG protein (Recombinant) (C-His) (STJP010507)	E. coli
STJP003541	Human PTH protein (Recombinant) (C-His) (STJP003541)	Mammalian Cells
STJP004112	Human MMP9 protein (Recombinant) (C-His) (STJP004112)	Mammalian Cells
STJP004678	Human THPO protein (Recombinant) (C-His) (STJP004678)	Mammalian Cells

Human DUSP1 protein (Recombinant) (C-His) (STJP014465)

General Information