| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 12.9pg/mL |
| Detection Limit: | 31.2-2000pg/mL |
| Short Description : | This DUSP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | DUSP1 |
| Gene ID: | 1843 |
| Uniprot ID: | DUS1_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. |
| Post Translational Modifications | Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. |
| Protein Name | Dual Specificity Protein Phosphatase 1 Dual Specificity Protein Phosphatase Hvh1 Mitogen-Activated Protein Kinase Phosphatase 1 Map Kinase Phosphatase 1 Mkp-1 Protein-Tyrosine Phosphatase Cl100 |
| Database Links | Reactome: R-HSA-112409 Reactome: R-HSA-5675221 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Dual Specificity Protein Phosphatase 1 ELISA kit Dual Specificity Protein Phosphatase Hvh1 ELISA kit Mitogen-Activated Protein Kinase Phosphatase 1 ELISA kit Map Kinase Phosphatase 1 ELISA kit Mkp-1 ELISA kit Protein-Tyrosine Phosphatase Cl100 ELISA kit DUSP1 ELISA kit CL100 ELISA kit MKP1 ELISA kit PTPN10 ELISA kit VH1 ELISA kit |
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Information sourced from Uniprot.org