Human DTD1 protein (Recombinant) (C-His) (STJP013727)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human DTD1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | DTD1 |
| Gene ID | 92675 |
| Uniprot ID | DTD1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro209 |
Additional Info
| Post Translational Modifications | Preferentially phosphorylated in cells arrested early in S phase. Phosphorylation in the C-terminus weakens the interaction with CDC45. |
| Function | Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes. An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis.rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality. |
| Protein Name | D-Aminoacyl-Trna Deacylase 1DtdDna-Unwinding Element-Binding Protein BDue-BGly-Trna(Ala DeacylaseHistidyl-Trna Synthase-Related |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmAssociated With Chromatin At Some Replication Origins Containing Functional Dna-Unwinding Elements |
| Alternative Protein Names | D-Aminoacyl-Trna Deacylase 1 proteinDtd proteinDna-Unwinding Element-Binding Protein B proteinDue-B proteinGly-Trna(Ala Deacylase proteinHistidyl-Trna Synthase-Related proteinDTD1 proteinC20orf88 proteinDUEB proteinHARS2 protein |
Information sourced from Uniprot.org