| Tissue Specificity | Strongly expressed in epidermis, less in lymph node and tongue. |
| Post Translational Modifications | |
| Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood. |
| Protein Name | Desmocollin-1Cadherin Family Member 1Desmosomal Glycoprotein 2/3Dg2/Dg3 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative ELISA Names | Desmocollin-1 ELISA kitCadherin Family Member 1 ELISA kitDesmosomal Glycoprotein 2/3 ELISA kitDg2/Dg3 ELISA kitDSC1 ELISA kitCDHF1 ELISA kit |
| output | |
Information sourced from Uniprot.org
