| Short Description : | Recombinant-Human DPT-C-Fc-His protein was developed from mammalian cells and has a target region of C-Fc-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 4% Sucrose, 4% mannitol, 0.02% Tween 80, pH 7.5. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | DPT |
| Gene ID: | 1805 |
| Uniprot ID: | DERM_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Gln19-Val201 |
| Post Translational Modifications | Sulfated on tyrosine residue(s). |
| Function | Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation. |
| Protein Name | DermatopontinTyrosine-Rich Acidic Matrix ProteinTramp |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Dermatopontin proteinTyrosine-Rich Acidic Matrix Protein proteinTramp proteinDPT protein |
Information sourced from Uniprot.org