| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human DNAJC27-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT, 2mM EDTA |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAJC27 |
| Gene ID: | 51277 |
| Uniprot ID: | DJC27_HUMAN |
| Immunogen Region: | 1-273aa |
| Accession Number: | NP_057628 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMEANMPK RKEPGRSLRI KVISMGNAEV GKSCIIKRYC EKRFVSKYLA TIGIDYGVTK VHVRDREIKV NIFDMAGHPF FYEVRNEFYK DTQGVILVYD VGQKDSFDAL DAWLAEMKQE LGPHGNMENI IFVVCANKID CTKHRCVDES EGRLWAESKG FLYFETSAQT GEGINEMFQT FYISIVDLCE NGGKRPTTNS SASFTKEQ |
| Tissue Specificity | Overexpressed in gastrointestinal cancers.expression correlates with later tumor-node-metastasis stages of colorectal cancers. |
| Function | GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. |
| Protein Name | Dnaj Homolog Subfamily C Member 27Rab And Dnaj Domain-Containing Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Dnaj Homolog Subfamily C Member 27 proteinRab And Dnaj Domain-Containing Protein proteinDNAJC27 proteinRABJS proteinRBJ protein |
Information sourced from Uniprot.org