Name: Human DKK2 protein (Recombinant) (N-His) (STJP006137)
SKU: STJP006137
Availability: InStock

Human DKK2 protein (Recombinant) (N-His) (STJP006137)

SKU:

STJP006137

£208.50 - £1,163.50

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Short Description :	Recombinant-Human DKK2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	May be proteolytically processed by a furin-like protease.
Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Protein Name	Dickkopf-Related Protein 2 Dickkopf-2 Dkk-2 Hdkk-2
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-3772470 Reactome: R-HSA-5339717
Cellular Localisation	Secreted
Alternative Protein Names	Dickkopf-Related Protein 2 protein Dickkopf-2 protein Dkk-2 protein Hdkk-2 protein DKK2 protein UNQ682 protein PRO1316 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP017809	Human DKK2 protein (Recombinant) (His-Tag) (STJP017809)	E.coli	SDS-PAGE/Denatured
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005250	Human FOXO1 protein (Recombinant) (N-His) (STJP005250)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005243	Human SIGLEC14 protein (Recombinant) (N-His) (STJP005243)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human DKK2 protein (Recombinant) (N-His) (STJP006137)

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