Human DJ-1/PARK7 protein (Recombinant) (His-Tag) (STJP019735)

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STJP019735
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DJ-1/PARK7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM EDTA, 1mM DTT, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPP1R14A
Gene ID: 94274
Uniprot ID: PP14A_HUMAN
Immunogen Region: 1-147aa
Accession Number: NP_150281
Immunogen: Human
Immunogen Sequence: MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP
Tissue Specificity Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Function Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Protein Name Protein Phosphatase 1 Regulatory Subunit 14a
17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1
Protein Kinase C-Potentiated Inhibitor Protein Of 17 Kda
Cpi-17
Database Links Reactome: R-HSA-5625740
Cellular Localisation Cytoplasm
Alternative Protein Names Protein Phosphatase 1 Regulatory Subunit 14a protein
17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1 protein
Protein Kinase C-Potentiated Inhibitor Protein Of 17 Kda protein
Cpi-17 protein
PPP1R14A protein
CPI17 protein
PPP1INL protein

Information sourced from Uniprot.org

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