Human DIO2 protein (Recombinant) (N-His) (STJP007664)

SKU:
STJP007664
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DIO2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DIO2
Gene ID: 1734
Uniprot ID: IOD2_HUMAN
Immunogen Region: Leu69-Leu269
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated by MARCHF6, leading to its degradation by the proteasome. Deubiquitinated by USP20 and USP33.
Function Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Protein Name Type Ii Iodothyronine Deiodinase
5dii
Dioii
Type 2 Di
Type-Ii 5'-Deiodinase
Database Links Reactome: R-HSA-350864
Reactome: R-HSA-9844594
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Protein Names Type Ii Iodothyronine Deiodinase protein
5dii protein
Dioii protein
Type 2 Di protein
Type-Ii 5'-Deiodinase protein
DIO2 protein
ITDI2 protein
TXDI2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP003417 Human TNFSF15 protein (Recombinant) (N-His) (STJP003417) E. coli
STJP011674 Human MZF1 protein (Recombinant) (N-His) (STJP011674) E. coli
STJP011681 Human PSME3 protein (Recombinant) (N-His) (STJP011681) E. coli

Related Products

!