Human DGKA protein (Recombinant) (N-His) (STJP007531)

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STJP007531
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DGKA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: DGKA
Gene ID: 1606
Uniprot ID: DGKA_HUMAN
Immunogen Region: Met1-Thr118
Immunogen: Homo sapiens (Human)
Function Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol.
Protein Name Diacylglycerol Kinase Alpha
Dag Kinase Alpha
80 Kda Diacylglycerol Kinase
Diglyceride Kinase Alpha
Dgk-Alpha
Database Links Reactome: R-HSA-114508
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Diacylglycerol Kinase Alpha protein
Dag Kinase Alpha protein
80 Kda Diacylglycerol Kinase protein
Diglyceride Kinase Alpha protein
Dgk-Alpha protein
DGKA protein
DAGK protein
DAGK1 protein

Information sourced from Uniprot.org

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