Human DESI1 protein (Recombinant) (His-Tag) (STJP018347)

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STJP018347
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DESI1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM DTT
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: DESI1
Gene ID: 27351
Uniprot ID: DESI1_HUMAN
Immunogen Region: 1-168aa
Accession Number: NP_056519
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEPPNLY PVKLYVYDLS KGLARRLSPI MLGKQLEGIW HTSIVVHKDE FFFGSGGISS CPPGGTLLGP PDSVVDVGST EVTEEIFLEY LSSLGESLFR GEAYNLFEHN CNTFSNEVAQ FLTGRKIPSY ITDLPSEVLS TPFGQALRPL LDSIQIQPPG GSSVGRPNGQ S
Function Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).
Protein Name Desumoylating Isopeptidase 1
Desi-1
Pppde Peptidase Domain-Containing Protein 2
Palmitoyl Protein Thioesterase Desi1
Polyubiquitinated Substrate Transporter
Post
S-Depalmitoylase Desi1
Database Links
Cellular Localisation Cytoplasm
Nucleus
Shuttles Between The Nucleus And The Cytoplasm
Exported From The Nucleus In A Xpo1/Crm1-Dependent Manner Via Its Nuclear Export Signal Motifs
Alternative Protein Names Desumoylating Isopeptidase 1 protein
Desi-1 protein
Pppde Peptidase Domain-Containing Protein 2 protein
Palmitoyl Protein Thioesterase Desi1 protein
Polyubiquitinated Substrate Transporter protein
Post protein
S-Depalmitoylase Desi1 protein
DESI1 protein
FAM152B protein
PPPDE2 protein

Information sourced from Uniprot.org

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