Tissue Specificity | |
Post Translational Modifications | |
Function | Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B. anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Blocks also herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment. |
Protein Name | Neutrophil Defensin 3Defensin - Alpha 3Hnp-3Hp-3Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2Hnp-2Hp-2Hp2 |
Database Links | Reactome: R-HSA-1461973Reactome: R-HSA-1462054 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Neutrophil Defensin 3 ELISA kitDefensin - Alpha 3 ELISA kitHnp-3 ELISA kitHp-3 ELISA kitHp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2 ELISA kitHnp-2 ELISA kitHp-2 ELISA kitHp2 ELISA kitDEFA3 ELISA kitDEF3 ELISA kit |
output | |
Information sourced from Uniprot.org