Human DcR3/TNFRSF6B protein (Recombinant) (His-Tag) (STJP018516)

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STJP018516
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human DcR3/TNFRSF6B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.4M urea
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF6B
Gene ID: 8771
Uniprot ID: TNF6B_HUMAN
Immunogen Region: 30-300aa
Accession Number: NP_003814.1
Immunogen: Human
Immunogen Sequence: VAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRL
Tissue Specificity Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Function Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 6b
Decoy Receptor 3
Dcr3
Decoy Receptor For Fas Ligand
M68
Database Links Reactome: R-HSA-5669034
Cellular Localisation Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 6b protein
Decoy Receptor 3 protein
Dcr3 protein
Decoy Receptor For Fas Ligand protein
M68 protein
TNFRSF6B protein
DCR3 protein
TR6 protein
UNQ186 protein
PRO212 protein

Information sourced from Uniprot.org

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