Human DBP (Vitamin D-Binding Protein) Antibody Pair (STJAP00230)

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STJAP00230-50
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Host: Rabbit/Rabbit
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This DBP antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Polyclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A or G.
Detection Purification: Protein A or G.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: GC
Gene ID: 2638
Uniprot ID: VTDB_HUMAN
Immunogen: Capture immunogen: Recombinant Human DBP protein.
Detection Immunogen: Recombinant Human DBP protein.
Post Translational Modifications Allele GC*1S is O-glycosylated at Thr-436. The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated. The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated.
Function Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Protein Name Vitamin D-Binding Protein
Dbp
Vdb
Gc Protein-Derived Macrophage Activating Factor
Gc-Maf
Gcmaf
Gc-Globulin
Group-Specific Component
Gc
Vitamin D-Binding Protein-Macrophage Activating Factor
Dbp-Maf
Database Links Reactome: R-HSA-196791
Cellular Localisation Secreted
Alternative Antibody Pair Names Vitamin D-Binding Protein antibody pair
Dbp antibody pair
Vdb antibody pair
Gc Protein-Derived Macrophage Activating Factor antibody pair
Gc-Maf antibody pair
Gcmaf antibody pair
Gc-Globulin antibody pair
Group-Specific Component antibody pair
Gc antibody pair
Vitamin D-Binding Protein-Macrophage Activating Factor antibody pair
Dbp-Maf antibody pair
GC antibody pair

Information sourced from Uniprot.org

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