Human DBP/GC protein (Recombinant) (C-His) (STJP013077)

Name: Human DBP/GC protein (Recombinant) (C-His) (STJP013077)
SKU: STJP013077-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP013077-100

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Short Description	Recombinant-Human DBP/GC-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Allele GC*1S is O-glycosylated at Thr-436. The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated. The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated.
Function	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Protein Name	Vitamin D-Binding Protein Dbp Vdb Gc Protein-Derived Macrophage Activating Factor Gc-Maf Gcmaf Gc-Globulin Group-Specific Component Gc Vitamin D-Binding Protein-Macrophage Activating Factor Dbp-Maf
Database Links	Reactome: R-HSA-196791
Cellular Localisation	Secreted
Alternative Protein Names	Vitamin D-Binding Protein protein Dbp protein Vdb protein Gc Protein-Derived Macrophage Activating Factor protein Gc-Maf protein Gcmaf protein Gc-Globulin protein Group-Specific Component protein Gc protein Vitamin D-Binding Protein-Macrophage Activating Factor protein Dbp-Maf protein GC protein

Information sourced from Uniprot.org