Human CYTH3 protein (Recombinant) (His-Tag) (STJP018754)

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STJP018754
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CYTH3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYTH3
Gene ID: 9265
Uniprot ID: CYH3_HUMAN
Immunogen Region: 1-399aa
Accession Number: NP_004218
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDEDGGG EGGGVPEDLS LEEREELLDI RRRKKELIDD IERLKYEIAE VMTEIDNLTS VEESKTTQRN KQIAMGRKKF NMDPKKGIQF LIENDLLQSS PEDVAQFLYK GEGLNKTVIG DYLGERDEFN IKVLQAFVEL HEFADLNLVQ ALRQFLWSFR LPGEAQKIDR MMEAFASRYC LCNPGVFQST DTCYVLSFAI IMLNTSLH
Tissue Specificity Almost absent from liver, thymus and peripheral blood lymphocytes.
Function Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization.
Protein Name Cytohesin-3
Arf Nucleotide-Binding Site Opener 3
Protein Arno3
General Receptor Of Phosphoinositides 1
Grp1
Ph - Sec7 And Coiled-Coil Domain-Containing Protein 3
Database Links Reactome: R-HSA-6811438
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Peripheral Membrane Protein
Cell Junction
Adherens Junction
Tight Junction
Translocates From The Cytosol To Membranes Enriched In Phosphatidylinositol 3
4
5-Trisphosphate
Alternative Protein Names Cytohesin-3 protein
Arf Nucleotide-Binding Site Opener 3 protein
Protein Arno3 protein
General Receptor Of Phosphoinositides 1 protein
Grp1 protein
Ph - Sec7 And Coiled-Coil Domain-Containing Protein 3 protein
CYTH3 protein
ARNO3 protein
GRP1 protein
PSCD3 protein

Information sourced from Uniprot.org

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