Human CYTH1 protein (Recombinant) (N-His) (STJP005449)

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STJP005449
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CYTH1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CYTH1
Gene ID: 9267
Uniprot ID: CYH1_HUMAN
Immunogen Region: Met1-His398
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated by SCF(FBXW11) E3 ubiquitin-protein ligase complex. Ubiquitination induces proteasomal degradation.
Function Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.
Protein Name Cytohesin-1
Ph - Sec7 And Coiled-Coil Domain-Containing Protein 1
Sec7 Homolog B2-1
Database Links Reactome: R-HSA-6811438
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasm
Cytosol
Cell Junction
Tight Junction
Adherens Junction
Colocalized With Tjp1 During Epithelial Polarization
Alternative Protein Names Cytohesin-1 protein
Ph - Sec7 And Coiled-Coil Domain-Containing Protein 1 protein
Sec7 Homolog B2-1 protein
CYTH1 protein
D17S811E protein
PSCD1 protein

Information sourced from Uniprot.org

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