| Short Description : | Recombinant-Human Cystatin B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | Enzyme Activity/SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50mM NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | The IC50 value is < 3.0nM. The inhibitory function of Cystatin B on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C. |
| Gene Symbol: | CSTB |
| Gene ID: | 1476 |
| Uniprot ID: | CYTB_HUMAN |
| Accession Number: | NP_000091 |
| Immunogen: | Human |
| Immunogen Region: | 1-98aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MMCGAPSATQ PATAETQHIA DQVRSQLEEK ENKKFPVFKA VSFKSQVVAG TNYFIKVHVG DEDFVHLRVF QSLPHENKPL TLSNYQTNKA KHDELTYF |
| Function | This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. |
| Protein Name | Cystatin-BCpi-BLiver Thiol Proteinase InhibitorStefin-B |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Cystatin-B proteinCpi-B proteinLiver Thiol Proteinase Inhibitor proteinStefin-B proteinCSTB proteinCST6 proteinSTFB protein |
Information sourced from Uniprot.org