Human CYP2C19 (Cytochrome P450 2C19) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014695)
SPECIFICATIONS
General Information
| Short Description | This CYP2C19 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.056ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | CYP2C19 |
| Gene ID | 1557 |
| Uniprot ID | CP2CJ_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates PUFA specifically at the omega-1 position. Catalyzes the epoxidation of double bonds of PUFA. Also metabolizes plant monoterpenes such as limonene. Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol. Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. Hydroxylates fenbendazole at the 4' position. |
| Protein Name | Cytochrome P450 2c19(R-Limonene 6-Monooxygenase(S-Limonene 6-Monooxygenase(S-Limonene 7-MonooxygenaseCypiic17Cypiic19Cytochrome P450-11aCytochrome P450-254cFenbendazole Monooxygenase4'-HydroxylatingMephenytoin 4-Hydroxylase |
| Database Links | Reactome: R-HSA-211981Reactome: R-HSA-211999Reactome: R-HSA-2142670Reactome: R-HSA-2142816Reactome: R-HSA-9749641 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
| Alternative ELISA Names | Cytochrome P450 2c19 ELISA kit(R-Limonene 6-Monooxygenase ELISA kit(S-Limonene 6-Monooxygenase ELISA kit(S-Limonene 7-Monooxygenase ELISA kitCypiic17 ELISA kitCypiic19 ELISA kitCytochrome P450-11a ELISA kitCytochrome P450-254c ELISA kitFenbendazole Monooxygenase ELISA kit4'-Hydroxylating ELISA kitMephenytoin 4-Hydroxylase ELISA kitCYP2C19 ELISA kit |
| output |
Information sourced from Uniprot.org