Tissue Specificity | |
Post Translational Modifications | |
Function | A cytochrome P450 monooxygenase involved in retinoid metabolism. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may modulate atRA signaling and clearance. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR.NADPH-ferrihemoprotein reductase). |
Protein Name | Cytochrome P450 2c18Cypiic18Cytochrome P450-6b/29c |
Database Links | Reactome: R-HSA-211981 |
Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
Alternative ELISA Names | Cytochrome P450 2c18 ELISA kitCypiic18 ELISA kitCytochrome P450-6b/29c ELISA kitCYP2C18 ELISA kit |
output | |
Information sourced from Uniprot.org