• Biotinylated Human/Cynomolgus/Rhesus macaque ROR1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human/Cynomolgus/Rhesus macaque ROR1 is greater than 95% as determined by SEC-HPLC.
  • Immobilized Biotinylated Human/Cynomolgus/Rhesus macaque ROR1 at 1 Mu g/ml (100 Mu l/Well) on the plate. Dose response curve for Anti-ROR1 Antibody, hFc Tag with the EC50 of 7. 7ng/ml determined by ELISA.

Human/Cynomolgus/Rhesus macaque ROR1 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001757)

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STJP001757

£618.50 - £1,909.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human/Cynomolgus/Rhesus macaque ROR1-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: ROR1
Gene ID: 4919
Uniprot ID: ROR1_HUMAN
Immunogen Region: Gln30-Glu403
Immunogen: DNA sequence encoding Human/Cynomolgus/Rhesus macaque ROR1 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells.
Protein Name Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1
Neurotrophic Tyrosine Kinase - Receptor-Related 1
Database Links Reactome: R-HSA-5140745
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Alternative Protein Names Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1 protein
Neurotrophic Tyrosine Kinase - Receptor-Related 1 protein
ROR1 protein
NTRKR1 protein

Information sourced from Uniprot.org

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