| Short Description : | Recombinant-Human Cyclophilin G/PPIG-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Enzyme Activity |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Specific activity is > 600nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin. |
| Gene Symbol: | PPIG |
| Gene ID: | 9360 |
| Uniprot ID: | PPIG_HUMAN |
| Accession Number: | AAH01555 |
| Immunogen: | Human |
| Immunogen Region: | 1-175aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF AVKHNKEFLL SMANRGKDTN GSQFFITTKP TPHLDGHHVV FGQVISGQEV VREIENQKTD AASKPFAEVR ILSCG |
| Tissue Specificity | Ubiquitous. |
| Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase GPpiase GPeptidyl-Prolyl Isomerase GCasp10Clk-Associating Rs-CyclophilinCars-CypCars-CyclophilinSr-CyclophilinSr-CypSrcypCyclophilin GRotamase G |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-9692916 |
| Cellular Localisation | Nucleus MatrixNucleus SpeckleColocalizes With Rna Splicing Factors At Nuclear Speckles |
| Alternative Protein Names | Peptidyl-Prolyl Cis-Trans Isomerase G proteinPpiase G proteinPeptidyl-Prolyl Isomerase G proteinCasp10 proteinClk-Associating Rs-Cyclophilin proteinCars-Cyp proteinCars-Cyclophilin proteinSr-Cyclophilin proteinSr-Cyp proteinSrcyp proteinCyclophilin G proteinRotamase G proteinPPIG protein |
Information sourced from Uniprot.org