| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CXCR2-N-His-KSI protein was developed from e.coli and has a target region of N-His-KSI. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | CXCR2 |
| Gene ID: | 3579 |
| Uniprot ID: | CXCR2_HUMAN |
| Immunogen Region: | Glu2-Lys48&Ala106-Lys120&Arg184-Arg208&Asp274-Arg294 |
| Immunogen: | Homo sapiens (Human) |
| Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
| Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Cdw128bGro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BIl-8 Receptor Type 2Cd Antigen Cd182 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | C-X-C Chemokine Receptor Type 2 proteinCxc-R2 proteinCxcr-2 proteinCdw128b proteinGro/Mgsa Receptor proteinHigh Affinity Interleukin-8 Receptor B proteinIl-8r B proteinIl-8 Receptor Type 2 proteinCd Antigen Cd182 proteinCXCR2 proteinIL8RB protein |
Information sourced from Uniprot.org