Host: |
HEK293 cells |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of 20mMTris, 500mMNaCl, pH 8.0 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: |
<1 EU/Mu g of the protein by LAL method. |
Gene Symbol: |
CXCL2 |
Gene ID: |
2920 |
Uniprot ID: |
CXCL2_HUMAN |
Immunogen Region: |
Ala35-Asn107 |
Immunogen: |
Recombinant Human CXCL2/MIP-2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ala35-Asn107) of Human CXCL2/MIP-2 (Accession #NP_002080.1) fused with No tag. |
Immunogen Sequence: |
LRSSSQNSSDKPVAHVVANH QAEEQLEWLSQRANALLANG MDLKDNQLVVPADGLYLIYS QVLFKGQGCPDYVLLTHTVS RFAISYQEKVSLLSAIKSPC PKDTPEGAELKPWYEPMYLG GVFQLEKGDLLSAEVNLPKY LDITESGQVYFGVIAL |
Post Translational Modifications | The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. |
Function | Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. |
Protein Name | C-X-C Motif Chemokine 2Growth-Regulated Protein BetaGro-BetaMacrophage Inflammatory Protein 2-AlphaMip2-Alpha Cleaved Into - Gro-Beta(5-73Gro-Beta-THematopoietic Synergistic FactorHsfSb-251353 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
Cellular Localisation | Secreted |
Alternative Protein Names | C-X-C Motif Chemokine 2 proteinGrowth-Regulated Protein Beta proteinGro-Beta proteinMacrophage Inflammatory Protein 2-Alpha proteinMip2-Alpha Cleaved Into - Gro-Beta(5-73 proteinGro-Beta-T proteinHematopoietic Synergistic Factor proteinHsf proteinSb-251353 proteinCXCL2 proteinGRO2 proteinGROB proteinMIP2A proteinSCYB2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance