Human CXCL16/SR-PSOX protein (Recombinant) (C-His) (STJP020131)

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STJP020131
£96.50 - £282.50
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: CXCL16
Gene ID: 58191
Uniprot ID: CXL16_HUMAN
Immunogen Region: Met1-Thr205
Immunogen: Recombinant Human CXCL16/SR-PSOX Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Thr205) of Human CXCL16/SR-PSOX Protein (Accession #NP_001094282.1) fused with His tag at the C-terminus.
Immunogen Sequence: MGRDLRPGSRVLLLLLLLLL VYLTQPGNGNEGSVTGSCYC GKRISSDSPPSVQFMNRLRK HLRAYHRCLYYTRFQLLSWS VCGGNKDPWVQELMSCLDLK ECGHAYSGIVAHQKHLLPTS PPISQASEGASSDIHTPAQM LLSTLQSTQRPTLPVGSLSS DKELTRPNETTIHTAGHSLA AGPEAGENQKQPEKNAGPTA RTSAT
Tissue Specificity Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
Post Translational Modifications Glycosylated.
Function Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Protein Name C-X-C Motif Chemokine 16
Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein
Sr-Psox
Small-Inducible Cytokine B16
Transmembrane Chemokine Cxcl16
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
Also Exists As A Soluble Form
Alternative Protein Names C-X-C Motif Chemokine 16 protein
Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein
Sr-Psox protein
Small-Inducible Cytokine B16 protein
Transmembrane Chemokine Cxcl16 protein
CXCL16 protein
SCYB16 protein
SRPSOX protein
UNQ2759 protein
PRO6714 protein

Information sourced from Uniprot.org

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