Human CXCL1/GRO-alpha protein (Recombinant) (C-hFC) (STJP002831)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human CXCL1/GRO-alpha Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala35-Asn107) of human CXCL1/GRO-alpha (Accession #NP_001502.1) fused with and a hFc tag at the C-terminus.
General Information
| Short Description | Recombinant-Human CXCL1/GRO-alpha-C-hFC protein was developed in hek293 cells using the region Ala35-Asn107. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.1 EU/Mu g |
Target Information
| Gene Symbol | CXCL1 |
| Gene ID | 2919 |
| Uniprot ID | GROA_HUMAN |
| Immunogen | Recombinant Human CXCL1/GRO-alpha Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala35-Asn107) of human CXCL1/GRO-alpha (Accession #NP_001502.1) fused with and a hFc tag at the C-terminus. |
| Immunogen Region | Ala35-Asn107 |
| Immunogen Sequence | ASVATELRCQCLQTLQGIHP KNIQSVNVKSPGPHCAQTEV IATLKNGRKACLNPASPIVK KIIEKMLNSDKSN |
Additional Info
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Growth-Regulated Alpha Protein proteinC-X-C Motif Chemokine 1 proteinGro-Alpha(1-73 proteinMelanoma Growth Stimulatory Activity proteinMgsa proteinNeutrophil-Activating Protein 3 proteinNap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 proteinCXCL1 proteinGRO proteinGRO1 proteinGROA proteinMGSA proteinSCYB1 protein |
Information sourced from Uniprot.org