Human CTSE protein (Recombinant) (C-His) (STJP013187)

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STJP013187-100
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Short Description :Recombinant-Human CTSE-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in 20mM MES, 150mM NaCl, pH 5.5.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:CTSE
Gene ID:1510
Uniprot ID:CATE_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ser20-Pro396
Post Translational Modifications Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57.
Function May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
Protein Name Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii
Database Links Reactome: R-HSA-2132295
Cellular Localisation Endosome
The Proenzyme Is Localized To The Endoplasmic Reticulum And Golgi Apparatus
While The Mature Enzyme Is Localized To The Endosome
Alternative Protein Names Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii protein
CTSE protein

Information sourced from Uniprot.org

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