Human CTDSP2 protein (Recombinant) (N-His) (STJP010621)

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STJP010621
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CTDSP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CTDSP2
Gene ID: 10106
Uniprot ID: CTDS2_HUMAN
Immunogen Region: Thr95-Pro271
Immunogen: Homo sapiens (Human)
Function Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Protein Name Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 2
Nuclear Lim Interactor-Interacting Factor 2
Nli-Interacting Factor 2
Protein Os-4
Small C-Terminal Domain Phosphatase 2
Small Ctd Phosphatase 2
Scp2
Database Links Reactome: R-HSA-381038
Cellular Localisation Nucleus
Alternative Protein Names Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 2 protein
Nuclear Lim Interactor-Interacting Factor 2 protein
Nli-Interacting Factor 2 protein
Protein Os-4 protein
Small C-Terminal Domain Phosphatase 2 protein
Small Ctd Phosphatase 2 protein
Scp2 protein
CTDSP2 protein
NIF2 protein
OS4 protein
SCP2 protein

Information sourced from Uniprot.org

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