Home
Research Area
Developmental Biology
Human CSF3R/G-CSF-R/CD114 protein (Recombinant) (C-His) (STJP002608)

Human CSF3R/G-CSF-R/CD114 protein (Recombinant) (C-His) (STJP002608)

SKU:

STJP002608

£97.50 - £291.50

Current Stock:

General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity:	Measured by its ability to inhibit the GCSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells.The ED₅₀ for this ettect is typically 31.5-126 ng/mL.

Gene Symbol:	CSF3R
Gene ID:	1441
Uniprot ID:	CSF3R_HUMAN
Immunogen Region:	Glu25-Pro621
Immunogen:	Recombinant Human CSF3R/G-CSF-R/CD114 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu25-Pro621) of human GCSF Receptor (Accession #NP_000751.1) fused with a 6×His tag at the C-terminus.
Immunogen Sequence:	ECGHISVSAPIVHLGDPITA SCIIKQNCSHLDPEPQILWR LGAELQPGGRQQRLSDGTQE SIITLPHLNHTQAFLSCCLN WGNSLQILDQVELRAGYPPA IPHNLSCLMNLTTSSLICQW EPGPETHLPTSFTLKSFKSR GNCQTQGDSILDCVPKDGQS HCCIPRKHLLLYQNMGIWVQ AENALGTSMSPQLCLDPMDV VKLEPPMLRTMDPSPEAAPP QAGCLQLCWEPWQPGLHIN

Post Translational Modifications	N-glycosylated.
Function	Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Protein Name	Granulocyte Colony-Stimulating Factor Receptor G-Csf Receptor G-Csf-R Cd Antigen Cd114
Database Links	Reactome: R-HSA-449836 Reactome: R-HSA-9616222 Reactome: R-HSA-9674555 Reactome: R-HSA-9705462
Cellular Localisation	Isoform 2: Secreted Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Granulocyte Colony-Stimulating Factor Receptor protein G-Csf Receptor protein G-Csf-R protein Cd Antigen Cd114 protein CSF3R protein GCSFR protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

reviews