| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.066ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This CS Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
CS |
| Gene ID: |
1431 |
| Uniprot ID: |
CISY_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Methylated. Trimethylation at Lys-395 by CSKMT decreases citrate synthase activity. In response to mitochondrial stress, the precursor protein is ubiquitinated by the SIFI complex in the cytoplasm before mitochondrial import, leading to its degradation. Within the SIFI complex, UBR4 initiates ubiquitin chain that are further elongated or branched by KCMF1. |
| Function | Key enzyme of the Krebs tricarboxylic acid cycle which catalyzes the synthesis of citrate from acetyl coenzyme A and oxaloacetate. |
| Protein Name | Citrate Synthase - MitochondrialCitrateSi-Synthase |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-71403Reactome: R-HSA-9837999Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative ELISA Names | Citrate Synthase - Mitochondrial ELISA kitCitrate ELISA kitSi-Synthase ELISA kitCS ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
