| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CRYM-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CRYM |
| Gene ID: | 1428 |
| Uniprot ID: | CRYM_HUMAN |
| Immunogen Region: | Met1-Lys314 |
| Immunogen: | Homo sapiens (Human) |
| Function | Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. |
| Protein Name | Ketimine Reductase Mu-CrystallinNadp-Regulated Thyroid-Hormone-Binding Protein |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Ketimine Reductase Mu-Crystallin proteinNadp-Regulated Thyroid-Hormone-Binding Protein proteinCRYM proteinTHBP protein |
Information sourced from Uniprot.org