Human CRHR2 protein (Recombinant) (N-His-SUMO) (STJP009643)

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STJP009643
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CRHR2-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CRHR2
Gene ID: 1395
Uniprot ID: CRFR2_HUMAN
Immunogen Region: Glu20-Lys108
Immunogen: Homo sapiens (Human)
Function G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Protein Name Corticotropin-Releasing Factor Receptor 2
Crf-R-2
Crf-R2
Crfr-2
Corticotropin-Releasing Hormone Receptor 2
Crh-R-2
Crh-R2
Database Links Reactome: R-HSA-373080
Reactome: R-HSA-418555
Reactome: R-HSA-422085
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Corticotropin-Releasing Factor Receptor 2 protein
Crf-R-2 protein
Crf-R2 protein
Crfr-2 protein
Corticotropin-Releasing Hormone Receptor 2 protein
Crh-R-2 protein
Crh-R2 protein
CRHR2 protein
CRF2R protein
CRH2R protein

Information sourced from Uniprot.org

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