| Tissue Specificity | Expressed in neutrophils (at protein level). Widely expressed. Expressed in the brain. Expressed in neutrophil precursors from bone marrow and peripheral blood. |
| Post Translational Modifications | |
| Function | Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation.induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit. Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL. |
| Protein Name | Copine-1Chromobindin 17Copine I |
| Database Links | Reactome: R-HSA-1483206Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell MembraneTranslocates To The Cell Membrane In A Calcium-Dependent Manner |
| Alternative ELISA Names | Copine-1 ELISA kitChromobindin 17 ELISA kitCopine I ELISA kitCPNE1 ELISA kitCPN1 ELISA kit |
| output | |
Information sourced from Uniprot.org
