Human CPLX2 (Complexin 2) Competitive ELISA Kit Ready-To-Use Kit (STJE0014481)
SPECIFICATIONS
General Information
| Short Description | This CPLX2 Competitive ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.084ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 2.5 hrs |
Target Information
| Gene Symbol | CPLX2 |
| Gene ID | 10814 |
| Uniprot ID | CPLX2_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia. |
| Post Translational Modifications | |
| Function | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis. |
| Protein Name | Complexin-2Complexin IiCpx IiSynaphin-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolPresynapseNucleusPerikaryonTranslocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal CellsIn Mast CellsCytosol And NucleusBecomes Enriched Near Plasma Membrane Following Stimulation |
| Alternative ELISA Names | Complexin-2 ELISA kitComplexin Ii ELISA kitCpx Ii ELISA kitSynaphin-1 ELISA kitCPLX2 ELISA kit |
| output |
Information sourced from Uniprot.org